[Results of sanitary epidemiologic examination of sanitary protective zone projects (discussion).

The authors defined main transgressions of law in sanitary epidemiologic well-being of population during sanitary epidemiologic examination of project materials for sanitary protective zones for enterprises, constructions and other objects, and during determination of their final dimensions.

[Study of the effectiveness of drugs in experimental models of poisoning neuropathy in malathion].

For the study developed of the experimental model of toxic neuropathy, using malathion. In this was examined the effectiveness of a course of administration of pharmacological agents with different mechanisms of action: gliatilin, galantamine, memantine, and the recombinant (PRD), nerve growth factor (NGF). From all agents only galantamine, PRD and NGF significantly reduced the degree of impairment of conduction of the sciatic nerve in rats after sub-acute poisoning with malathion.

[Evaluating biomarkers of exposure to electric welding aerosol].

Biologic monitoring data in electric welders revealed reliable correlation between manganese concentration in the whole blood and manganese concentrations in the workplace air. The chronic manganese intoxication patients showed reliable lower levels of urinary iron, cobalt and manganese vs. those values in the reference group.

[Peculiarities of nervous system functional state in electric welders exposed to manganese compounds].

Peculiarities of nervous system functional state in electric welders exposed to manganese compounds. To evaluate nervous system functional state in electric welders exposed to manganese compounds, the authors conducted transverse study with matched pairs. The electric welders' tests for response rate, diadochokinesis and grasping power were not reliable. No changes were found in tremor characteristics and posture steadiness. Bradykinesia appeared to prevail in welders.

Blood concentrations of persistent toxic substances in the indigenous communities of the Russian Arctic.

OBJECTIVES: Investigation was carried out within the framework of the large-scale international project "Persistent Toxic Substances (PTS), Food Security and Indigenous People of the Russian North" under RAIPON/AMAP/GEF aegis. Objectives of the project are to obtain comprehensive information on exposure of indigenous populations to contaminants through food chains (and other sources), and to investigate the possible health effects connected to this exposure. Four regions of Russia are involved in the project: Kola Peninsula (Murmansk oblast), Nenetsk okrug (Pechora river basin), Taimyr Peninsula, Chukotka Peninsula. METHODS: Questionnaire and paired sampling of maternal/cord blood among indigenous women at childbirth (more than 250 persons) as well as among general indigenous population (more than 1,400 persons), additionally breast milk sampling of lactating women (more than 50 persons) in Chukotka was conducted. About 700 blood samples have been analyzed at the Center for Environmental Chemistry, SPA "Typhoon" (Obninsk, Russia), the Regional Center "Monitoring of the Arctic", RCMA (St. Petersburg, Russia), the Norwegian Institute for Air Research, NILU (Tromso, Norway) and at INSPQ (Sainte-Foy, Quebec, Canada). RESULTS AND CONCLUSIONS: On the whole, PTS in human blood of the Russian Arctic natives are similar to those in the coastal areas of Greenland and Canada, and for some POPs such as toxaphenes and mirex, these levels are lower.

[Features of occupational fluorosis course]. / Osobennosti techeniia professional'nogo fliuoroza.

Analysis of X-ray signs in 397 patients suffering from fluorosis revealed degenerative and dystrophic lumbar disorders in 94%, calcified anterior longitudinal ligament in 65%, various changes (epicondylosis, periarthrosis and arthrosis deformans) in 91%. Locomotory disorders appeared systemic, multiple and symmetrical.